NOTCH2 anticorps (APC)

N° du produit ABIN2658816

Cet anticorps Souris Monoclonal détecte spécifiquement NOTCH2 dans BCA. Il présente une réactivité envers Humain.

Aperçu rapide pour NOTCH2 anticorps (APC) (ABIN2658816)

Antigène: NOTCH2 (Notch 2 (NOTCH2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NOTCH2 est conjugé à/à la APC

Application: Biochemical Assay (BCA)

Clone: MHN2-25

Détail du produit anti-NOTCH2 anticorps (APC)

Purification: The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur NOTCH2

Antigène: NOTCH2 (Notch 2 (NOTCH2))

Autre désignation: Notch 2

Sujet: The Notch receptors are a type I transmembrane protein family that share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. They are highly conserved from invertebrates to mammals. Notch 1 and Notch 2 exhibit the highest structural similarity among the four mammalian Notch receptors (Notch 1-4). Notch 1 and Notch 2 are reported to be functionally redundant. Notch 2 is expressed by Pre-B cells, double negative, and CD8 single positive thymocytes, brain, and lung cells. Notch 2 functions as a receptor for Jagged and Delta ligands and may play a role in vascular, renal and hepatic development.

Pathways: Signalisation Notch, Stem Cell Maintenance